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Metronidazole is used alone or in combination with other antibiotics in treating abscesses in the liver, pelvis, abdomen and brain caused by susceptible anaerobic bacteria. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Metronidazole is a valuable antibiotic and is generally well tolerated with appropriate use. The first trimester of pregnancy. Metronidazole is one of the rare examples of a drug developed against a parasite which has since gained broad use as an antibacterial agent.
